Skin Education

Skincare Tips

Botox Aftercare: What to Avoid the First 24 Hours

Medically reviewed by Anna Heck, PA-C, MPAS, CAQ-Derm · 4 min read

Botox and other neuromodulators are quick, in-office procedures with minimal downtime — but the first 24 hours after treatment matter more than people expect. A few simple precautions help the product settle where it's supposed to and reduce the chance of bruising or unwanted side effects.

Right After Your Appointment

  • Stay upright for 4 hours. Avoid lying down flat, bending over for extended periods, or sleeping. Gravity helps keep the product localized to the treated muscles.
  • Skip the gym. Avoid strenuous exercise for the rest of the day — increased blood flow and elevated heart rate can theoretically cause the product to spread beyond the treated area.
  • Don't rub or massage the treated area. This includes facials, massages, or even pressing on the area to check how it feels. Let it settle undisturbed.
  • Avoid touching your face unnecessarily for the first few hours, beyond normal, gentle washing.

What to Avoid for the First 24 Hours

  • Alcohol — it thins the blood and increases bruising risk
  • Blood thinners you don't need — if you take aspirin, ibuprofen, or fish oil for a non-medical reason, ask your provider whether pausing briefly around your appointment makes sense; never stop a medication prescribed for a medical condition without talking to the prescribing doctor first
  • Extended heat exposure — saunas, hot yoga, and very hot showers can increase swelling and redness
  • Makeup immediately after treatment — most providers recommend waiting several hours to reduce the risk of irritating the injection sites

What's Normal to Experience

  • Small red bumps at injection sites that resolve within an hour or two
  • Mild tenderness or bruising, more likely if you're on blood thinners or have a bruising tendency
  • No visible change yet — results typically begin appearing within 3-5 days and reach full effect by around two weeks

What's Not Normal — Contact Your Provider If You Notice

  • Drooping of the eyelid or eyebrow that develops over the following days
  • Difficulty swallowing or breathing
  • Severe or worsening pain
  • Signs of infection (increasing redness, warmth, or pus at injection sites)

These are uncommon, but worth calling your provider about right away if they occur.

When Will I See Results?

Most people notice initial softening within 3-5 days, with full results typically visible by 10-14 days. If you have an event you want to look your best for, plan your appointment at least two weeks ahead to allow full results to develop and to leave time for a touch-up if needed.

How Long Does Botox Last?

Results typically last three to four months before the treated muscles gradually regain movement and a touch-up is needed to maintain the effect.

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Frequently Asked Questions

Can I lie down after getting Botox?

It's best to stay upright for about 4 hours after treatment. Lying down too soon can theoretically allow the product to shift away from the intended treatment area.

Can I exercise after Botox?

Avoid strenuous exercise for the rest of the day. Increased blood flow and heart rate can increase the risk of bruising and may affect how the product settles.

Can I drink alcohol after Botox?

It's best to avoid alcohol for at least 24 hours, since it thins the blood and increases the risk of bruising at injection sites.

How long until I see Botox results?

Most people notice initial changes within 3-5 days, with full results typically visible by 10-14 days. Results generally last three to four months.

Is it normal to have bruising after Botox?

Mild bruising or tenderness at injection sites is common, especially for people on blood thinners or with a natural bruising tendency. It typically resolves within a few days. Significant or worsening pain, or drooping that develops afterward, should be reported to your provider.