OnSpot Dermatology — Brick & Mortar Office

Orlando Office

1131 South Orange Avenue, Orlando, FL 32806

Walk-ins welcome, based on same-day availability — or book ahead to guarantee your spot.

Prefer a mobile clinic visit? Find when OnSpot will be near you

250K+

Patients Seen Since 2021

50K+

Cancers Found & Treated

Jessica Campestrini, PA-C

Jessica Campestrini, PA-C

Physician Assistant, Certified · English & Portuguese

Dr. Peter Mattei, MD

Dr. Peter Mattei, MD

Mohs Surgeon

Insurance Plans We Accept
AARP United Healthcare Medicare PPO/HMO
Aetna
Ambetter
Cigna
Evolutions Health Plan
First Health Medical PPO
Humana
Imagine360
Medicaid
Medicare
Molina
Multiplan / PHCS Network
Partners Direct Health Plan
Priority Health Plan
Prominence Health Plan
Tricare
UnitedHealthCare
VACCN
Wellmed

Insurance plans and coverage details change frequently — call us at (941) 444-0011 to confirm your specific plan before your appointment.

Office Information

OnSpot Dermatology Orlando

Our Central Florida office serves Orange, Osceola, Lake, and Brevard County patients. Located along South Orange Ave in the heart of Orlando.

Address

1131 South Orange Avenue, Orlando, FL 32806

Get Directions →

Phone

(941) 444-0011

(941) 444-0011

Hours

Monday – Friday, 8:00 AM – 5:00 PM

Parking

Street and lot parking available nearby.

Get Directions

1131 South Orange Avenue, Orlando, FL 32806

Insurance Accepted

We accept most major insurance plans at our Orlando office. Call to verify your specific coverage before your visit.

(941) 444-0011

Also Serving the Community

In addition to this office, OnSpot's Derma Drive® mobile clinic visits communities, country clubs, and workplaces throughout the Orlando area.

Request a mobile clinic visit →

Orlando Health Partnership

OnSpot Dermatology works closely with Orlando Health — our mobile Derma Drive® clinic visits 13 Orlando Health campuses, and we coordinate directly with their team on patient referrals when specialist or hospital-based care is needed.

Take a Look Inside

Our Orlando Office

Entrance of the OnSpot Dermatology Orlando office
OnSpot Dermatology Orlando front desk team
Exam room at the OnSpot Dermatology Orlando office
Exam room at the OnSpot Dermatology Orlando office

At This Location

Services Available in Orlando

Skin Cancer Exam

Early detection saves lives. Our dermatology professionals perform full-body skin cancer screenings and exams to identify suspicious moles, lesions, and early-stage skin cancers before they progress. If something suspicious is found, a skin biopsy can often be performed in the same visit.

Acne Treatment

Persistent acne needs more than over-the-counter solutions. Our dermatology professionals diagnose the root cause and build a customized treatment plan — from topical retinoids to oral antibiotics to advanced procedures.

Photodynamic Therapy (PDT)

Photodynamic therapy (PDT) combines a topical photosensitizing medication with targeted light exposure to destroy abnormal cells. It's one of the most effective non-surgical treatments for actinic keratoses and precancerous lesions.

Mole, Lesion & Skin Tag Removal

Not every mole needs to be removed, but suspicious lesions should be evaluated promptly. Our dermatology professionals assess moles using dermoscopy and remove concerning lesions safely with minimal scarring. We also remove benign growths like skin tags and cysts in the same visit, using techniques such as shave excision, electrocautery, or cryotherapy depending on the growth.

Excisions & Mohs Surgery

Mohs micrographic surgery is the gold standard for treating basal cell and squamous cell carcinomas. With a 99% cure rate for primary tumors, it removes cancer layer by layer while sparing maximum healthy tissue.

Eczema Treatment

Eczema (atopic dermatitis) is a chronic inflammatory skin condition that requires ongoing management. Our dermatology professionals provide evidence-based treatment plans including topical therapies, biologics, and trigger management.

Psoriasis Treatment

Psoriasis is an immune-mediated skin disease causing rapid skin cell buildup, resulting in scaling, inflammation, and discomfort. Modern treatments — including biologics — can achieve clear or nearly clear skin for most patients.

Neuromodulators & Cosmetic Injectables

Neuromodulator injections (botulinum toxin) relax targeted facial muscles to soften dynamic wrinkles — crow's feet, forehead lines, frown lines, and more. Results are natural-looking when administered by a skilled provider.

Telemedicine Appointments

OnSpot offers secure video telemedicine appointments for new and established patients — especially useful for ongoing conditions like acne, eczema, and psoriasis that need regular care, not just a single visit. Also available for rash evaluation, prescription refills, and more. Available statewide in Florida.

Eczema & Psoriasis Treatment

Eczema and psoriasis are both chronic, inflammatory skin conditions that flare and subside over time — and they're commonly confused with each other. Our dermatology professionals diagnose which one you actually have and build a treatment plan around it, from topical therapies to modern biologics.

Rosacea Treatment

Rosacea is a chronic inflammatory condition that causes facial redness, visible blood vessels, and sometimes acne-like bumps — often mistaken for regular acne or sun sensitivity. Our dermatology professionals diagnose the specific type of rosacea you have and build a treatment plan to calm flares and reduce visible redness over time.

Ready to Book at Our Orlando Office?

Same-week appointments available. Most insurance plans accepted.

Prefer a mobile clinic visit? Find when OnSpot will be near you